WANECAM 1

About WANECAM 1

Malaria is a significant threat to public health and economic development in sub-Saharan Africa The goals of malaria control cannot be achieved without strong involvement from scientists who are directly affected by this terrible disease in their daily lives The participation of African scientists in international malaria research efforts remains insufficient.

The European and Developing Countries Clinical Trials Partnership (EDCTP) is an important initiative of the European Union that works to strengthen the Africa-Europe partnership through the clinical development of vaccines and medicines, researcher training, and institutional framework promotion.

The development of a West African sub-region (Burkina Faso, Gambia, Guinea, and Mali), equipped with clinical trial sites, laboratories, and cutting-edge research teams capable of conducting Phase I-IV trials for new malaria drugs.

Development of antimalarial drugs
Personnel training
Network partnership
Development of laboratories and field sites for research

Coordination : Mali

African Members

Malaria Research and Training Center (MRTC), Université de Bamako, Bamako, Mali
National Center for Research and Training on Malaria (CNRFP), Ouagadougou, Burkina Faso
National Center for Training and Research in Rural Health (CNFRSR), Mafèrinyah, Guinea Mrc Gambia, Gambia

European Members

Research Unit on Malaria, Claude Bernard University, Lyon, France
Malaria Research Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
London School of Hygiene & Tropical Medicine, London, United Kingdom
Malaria Group (molecular epidemiology), University of Heidelberg School of Medicine, Heidelberg, Germany

Collaborators

NameRole(s) within the ConsortiumInstitutionCountry
Abdoulaye DjimdéProject Coordinator, PhD/MSc SupervisorUniversity of Bamako, Molecular Epidemiology and Drug Resistance Unit & Malaria Research and Training Centre, DEAP, FMPOSBamako, Mali
Ogobara DoumboCollaborator
Issaka SagaraCollaborator, IP Study Site & PhD student
Mahamadou Ali TheraCollaborator
Alassane DickoMain responsible for Work Package 3
Kassoum KayentaoCollaborator
Oumou NiaréCollaborator
Adama DaoCollaborator
Aminatou KonePhD student
Mamadou TeketeDoctoral student
Sirima B. SodiomonMain responsible for Work Package 2, IP Study Site & MSc SupervisorCentre National de Recherche et de Formation sur le Paludisme (CNRFP)Ouagadougou,Burkina Faso
Issaka SoulamaCollaborator & Study Site IP
Espérance CoulibalyCollaborator
Jean-Baptiste Bibié YaroCollaborator
Issa NébiéCollaborator
Alfred TionoCollaborator
Jean-Bosco OuedraogoCollaborator & Study Site IPIRSS, Regional Directorate of the WestBobo-Dioulasso, Burkina Faso
Issaka ZongoCollaborator
Esperance OuedraogoMaster’s student
Abdoul Habib BeavoguiCollaborator, IP Study Site & MSc SupervisorCentre National de Formation et de Recherche en Santé Rurale (CNFRSR) de MafèrinyahConakry, République de Guinée
Mamadou Malal DialloCollaborator
Alexandre DelamouCollaborator
Moussa SyllaMaster’s student
Elizabeth DiawaraMaster’s student
David NwankmaCollaborator
Steffen BormannCollaborator & Thesis Director (PhD)University of Heidelberg School of MedicineHeidelberg, Allemagne
Stephane PicotCollaboratorUniversité Claude Bernard Lyon 1Lyon, France
Jean GaudartPhD SupervisorUniversite Aix-Marseille, SESSTIMMarseille, France
Anders BjörkmanMain responsible for Work Package 4 & Thesis Supervisor (PhD)Karolinska University HospitalStockholm, Suède
Jose Pedro GillCollaborator & Thesis Director (PhD)
Colin SutherlandCollaboratorLondon School of Hygiene & Tropical Medicine (LSHTM)Londres, Royaume-Uni

Countries

Burkina Faso

The National Center for Research and Training on Malaria (CNRFP) is part of the General Secretariat of the Ministry of Health of Burkina Faso. It was founded in 1982 with the financial and technical support of the General Directorate for Development Cooperation, Italian Ministry of Foreign Affairs (DOCS-MAE). The center is one of two main malaria research establishments in the country.

France

Our research is dedicated to the analysis of the molecular mechanisms involved in the growth of Plasmodium falciparum and Plasmodium vivax in vitro, pathogenesis in mice and humans, and resistance to antimalarial drugs. Our main objective is to describe the genes involved in parasite apoptosis, and parasite-induced apoptosis in human cells in order to understand their regulation and control their expression.

Germany

The Heidelberg University Hospital with the Faculty of Medicine are internationally recognized centers for patient care, research and training.

Guinea

The Mafèrinyah center was created on November 16, 1988 and was named in April 1992 as the “National Center for Training and Research in Rural Health (CNFRSR)” Jean SENECAL under the aegis of the Guinean government with the help from the Brittany region (France), the French Ministry of Cooperation, local representatives of Unicef ​​​​and the World Health Organization.

Mali

The MRTC is at the Department of Epidemiology of Parasitic Diseases (DEAP), at the Faculty of Medicine, Pharmacy and Odonto-Stomatology (FMPOS) of the University of Bamako in Mali. The MRTC has a staff of more than 150 permanent staff, more than 50 of whom are doctoral-level scientists. We are involved in all aspects of malaria research. All work at the MRTC is directed towards developing tools and testing appropriate strategies for the control of malaria and reduction of the disease burden due to this disease. Ongoing studies include malaria epidemiology, entomology, drug resistance, vaccine development, drugs and diagnostic tools, pathogenesis and malaria in pregnancy.

Sweden

The research at our unit at Karolinska Institutet revolves around chemotherapy approaches for the management of Plasmodium falciparum malaria. The group has been testing major artemisinin combination therapies (ACTs) through efficacy and effectiveness clinical trials in Africa.

Gambia

Established in The Gambia in 1947, the MRC is the UK’s single largest investment in medical research in a developing country. The Unit’s research focuses on infectious diseases of immediate concern to The Gambia and the continent of Africa, with the aim of reducing the burden of illness and death in the country and the developing world as a whole.

United Kingdom

The London School of Hygiene & Tropical Medicine is Britain’s national school of public health and a leading postgraduate institution worldwide for research and postgraduate education in global health. Part of the University of London, the London School is the largest institution of its kind in Europe with a remarkable depth and breadth of expertise encompassing many disciplines. It is one of the highest-rated research institutions in the UK.

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